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It is an opportunity for us to reflect on the language and ideas that represented each year. So, take a stroll down memory lane to remember all of our past Word of the Year selections. Change It wasn’t trendy , funny, nor was it coined on Twitter , but we thought change told a real story about how our users defined Unlike in , change was no longer a campaign slogan. But, the term still held a lot of weight. Here’s an excerpt from our Word of the Year announcement in


Can botanicals be dietary supplements? What is a botanical? Herbs are a subset of botanicals. Products made from botanicals that are used to maintain or improve health may be called herbal products, botanical products, or phytomedicines.

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Professional word nerd, amateur francophile, home cook, carbohydrate enthusiast and person who is obnoxious about yoga. I wandered around my local Ralphs for a few minutes looking for poultry that hadn’t already been turned into individually shrink-wrapped meat units before asking for help. The gentleman I flagged down blinked a few times at my question. I took it home, rubbed it in butter and herbs, shoved a lemon half up its butt, and roasted it low and slow for the majority of the day.

It turned out okay. For all the work it took, it certainly wasn’t notably better than a store-bought rotisserie chicken, and with the other ingredients factored in, it cost significantly more. In retrospect, it’s not hard to understand why the fellow at Ralphs thought I was weird. But in most cases, preparing meals from scratch is significantly cheaper than buying them pre-made. What makes rotisserie chickens the exception? Grocery Store Economics The answer lies in the curious economics of the full-service supermarket.

For instance, the Gelson’s by me offers, among other amenities, a hot bar, a salad bar, a bakery, a gelateria, a full-service deli and an olive bar, because we live in L. But how can it afford to put out all of this food fresh every day?

A History: ’s Word of the Year

Abstract To explore the associations among dating violence DV , aggression, relationship power, and depressive symptoms. Design A cross-sectional survey secondary analysis. Setting An urban, school based health center, October, through May, Methods Descriptive and bivariate analyses were conducted to illustrate patterns and associations among variables.

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A dog will bound out from behind the r News Briefs: AP — Roswell police are searching for a suspect who they say shot at an off-duty officer outside his home on New Year s Eve. Police say the office Chris Saturday Evening Forecast The storm has moved out and behind it skies have cleared out, but the cold temperatures are still in place. As failing grades pile up some kids lose motivation, and too often, they drop out.

Girl, 7, says she survived Ky. AP A 7-year-old girl survived a plane crash that killed four people Friday night, and the disoriented little girl walked Page 3 of Mark s Friday Evening Weather Report The Winter Storm continues to move across New Mexico and it s dumping snow for a good part of southern and eastern New Mexico right now. Here s your chance. KRQE — We all know the state question is red or green. Oregon vs Florida State The first-ever college football semifinal took place Jan.

Susana Martinez is starting her second term in office. We make sure all of our hydraulic lig Left out in the cold: Now they re working to figure out who Photos:

A History: ’s Word of the Year

Licence This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. Abstract In contrast to dominant mode of ecological transition in the evolution of marine mammals, different lineages of toothed whales Odontoceti have repeatedly invaded freshwater ecosystems during the Cenozoic era.

Here we describe a new genus and species of fossil inioid, Isthminia panamensis, gen.

Hi, My name is Holly I’m pretty outgoing most of the time, however I do enjoy a quiet conversation, or a nice evening at home. I love hanging out with good friends and having crazy adventures.

In a world where teenagers can only be sidekicks, Spiderman stands out. Spiderman was created by Stan Lee writer and Steve Ditko artist. At the time of his creation, superheroes were all adults; and teenagers were only sidekicks like Robin and Bucky. Thus, his creators wanted to make a superhero that teens can relate to. This made Spiderman a hit to teenagers and young adults which fueled his success. However, during those times, he was called “Spider-Man”.

A hyphen was included in his name to avoid confusion with Superman of DC Comics. On August , Spiderman made his first appearance in the comics Amazing Fantasy Spiderman- whose real identity is Peter Parker- was a high school student when the story began.

Kevin Durant Allegedly Dating Warriors Reporter Ros Gold

Filed under Pagadian City The Philippines, being a country archipelago of islands and seas, have naturally wonderful beaches, some of which are famous the world over. Beaches like Puerto Galera, Boracay, and the various beaches in Cebu rake in tourists from around the world all year round because of their pristine and cool blue waters and fine, white-sand shores. However, if one will just look around more, they will find that there are other less-known but equally beautiful beach spots in other parts of the Philippines.

In Pagadian, in particular, there are beaches and islands that will make one believe that there is such a thing as a secluded paradise on Earth. A nice place to start would be the Dao-Dao Islands some seven to ten minutes away from the seaport, when riding a motorboat.

Much less is known of MPK functions in nonvascular land plants such as the moss Physcomitrella patens. Here, we provide evidence for a signaling pathway in P. patens required for immunity triggered by pathogen associated molecular patterns (PAMPs).

Is there a way to exploit the metabolic quirk of cancer? Can we starve the disease? Personally and professionally I have a great interest in cancer, so when Tim asked if I could write something about cancer that was: Yes, I realize this is sort of cheating on my 1, word promise. Cancer — a collection of cells in our bodies that grow at roughly normal speeds, but that do not respond appropriately to cell signaling.

Contrary to popular misconception, cancers cells do not grow especially fast relative to non-cancer cells. Metabolism — the process of converting the stored energy in food chemical energy contained mostly within the bonds of carbon and hydrogen atoms into usable energy for the body to carry out essential and non-essential work e. As its name suggests, this molecule has three tri phosphates.

Is there a way to exploit the metabolic quirk of cancer?

In football, the players are in pads and helmets, while even the closest seats are a good distance from the field. Baseball has the dugout, which serves as an exclusive sanctuary for players and the coaching staff. Rihanna has been a long-time LeBron James fan, and is outward in her support for the Cavs over the Warriors.

Photosynthetic organisms have both non-enzymatic and enzymatic mechanisms to protect themselves against ROS.A plethora of enzymes are able to detoxify or prevent the formation of O 2 · − and H 2 O 2 in cyanobacteria, including superoxide dismutases, peroxiredoxins, flavodiironproteins,, catalases, and Dps proteins (DNA binding proteins from starved cells).

Abstract MAP kinase MPK cascades in Arabidopsis thaliana and other vascular plants are activated by developmental cues, abiotic stress, and pathogen infection. Much less is known of MPK functions in nonvascular land plants such as the moss Physcomitrella patens. Here, we provide evidence for a signaling pathway in P. This pathway induces rapid growth inhibition, a novel fluorescence burst, cell wall depositions, and accumulation of defense-related transcripts.

Knockout lines of MPK4a appear wild type but have increased susceptibility to the pathogenic fungi Botrytis cinerea and Alternaria brassisicola. In contrast, abscisic acid treatment or osmotic stress of P. Signaling via MPK4a may therefore be specific to immunity, and the moss relies on other pathways to respond to osmotic stress. Plants and animals have evolved surface-localized, pattern recognition receptor kinases PRRs that detect conserved pathogen-associated molecular patterns PAMPs; Zipfel, However, the contributions of single MPKs in Arabidopsis immunity or stress responses remain unclear due to the pleiotropic phenotypes of some of their loss-of-function mutants and to their potential redundancies Petersen et al.

The Arabidopsis mpk4 loss-of-function mutants exhibit dwarfism and ectopically express defense responses but are suppressed by mutation of SUMM2, which encodes a resistance R protein Zhang et al. This indicates that the MPK4 pathway is a target of pathogen effectors and is monitored by SUMM2, in line with the guard hypothesis of effector-triggered immunity in plant-pathogen evolution Jones and Dangl, ; Zhang et al.

The moss Physcomitrella patens is a bryophyte, an early branch of land plants Zimmer et al. However, PTI components have not been identified in P. They represent a basal set of pathways whose functions may be assessed by their targeted knockouts KOs or knockins KIs via homologous recombination, a genetic approach unavailable in vascular plants.

hukum or HARAM?

Xianghua by Robvalue Version: It also includes information about the moves such as special properties, whether they hit high, mid or low, their damage, range and speed. They are presented in an organised list so that along with the information I have provided you should be able to have a quick reference guide to all Xianghua’s moves and transitions.

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Morris Show more https: The presence of a vertical supranuclear gaze palsy and prominent postural instability with falls in the first year of symptoms leads to a diagnosis of clinically probable PSP, and the presence of the balance disorder with slowing of vertical saccades or an isolated supranuclear gaze palsy leads to a diagnosis of clinically possible PSP. Magnetic resonance imaging MRI is helpful in excluding structural lesions and in established PSP often shows midbrain and superior cerebellar peduncular atrophy, which can be used to distinguish PSP from Parkinson’s disease PD and multiple system atrophy MSA associated with parkinsonism.

Pathologically, PSP involves the deposition of neurofibrillary tangles NFTs , gliosis, and cell loss in a specific distribution, particularly affecting the subthalamic nucleus, globus pallidus, substantia nigra pars compacta and reticulata , pretectal area of the midbrain, and basis pontis. Cerebrospinal fluid tau analysis may become a biomarker, which might be useful in diagnosing PSP or in tracking the response to disease-modifying therapies.

The molecular genetics and treatment methods of PSP are also discussed in the chapter. Check if you have access through your login credentials or your institution.


A WORD or two of explanation will probably be necessary in order to see the full meaning of this great promise. The Prophet has just been describing a vision of judgment which he saw, in which the high priest, as representative of the nation, stood before the Angel of the Lord as an unclean person. And then follow a series of promises, of which the climax is the one that I have read. And so the promise of my text, in highly figurative fashion, is that of free and unrestrained approach to God, of a life that is like that of the angels that stand before His Face.

So, then, the words suggest to us, first, what a Christian life may be.

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Abstract Plant innate immunity relies on successful detection of microbe-associated molecular patterns MAMPs of invading microbes via pattern recognition receptors PRRs at the plant cell surface. Live cell imaging and microsomal fractionation consistently revealed the plasma membrane localization of these proteins in rice cells. Transcription of these two genes could be induced rapidly upon exposure to bacterial pathogens or diverse MAMPs. Accordingly, silencing of either LYP specifically impaired PGN – or chitin- but not LPS -induced defense responses in rice, including reactive oxygen species generation, defense gene activation, and callose deposition, leading to compromised resistance against bacterial pathogen Xanthomonas oryzae and fungal pathogen Magnaporthe oryzae.

Interestingly, pretreatment with excess PGN dramatically attenuated the alkalinization response of rice cells to chitin but not to flagellin; vice versa, pretreatment with chitin attenuated the response to PGN , suggesting that PGN and chitin engage overlapping perception components in rice. Due to lack of specialized immune cells, plants have evolved an elegant capability to trigger complex immune responses against invading microbes upon perception of microbe-associated molecular patterns MAMPs , which are molecular signatures of whole classes of microbes Ausubel, During pattern-triggered immunity, recognition of different MAMPs by their cognate pattern recognition receptors PRRs at the plant cell surface and subsequent signal transduction across the plasma membrane are pivotal steps, which eventually lead to overlapping and specific defense responses to counteract invasion of different pathogens Boller and Felix, Most of the known MAMPs , regardless of their microbial origin, could be categorized into either polypeptide type or carbohydrate type.

LPS is an outer membrane glycoconjugate from Gram-negative bacteria that is composed of a lipid A moiety, a covalently linked oligosaccharide core, and a polysaccharide moiety. It was found that the oligosaccharide core and the lipid A within LPS could induce distinct defense responses in plants, suggesting that plant cells likely sense sugar and lipid structures within LPS through different receptors Silipo et al. Although the LPS receptors have been well characterized in animals Ronald and Beutler, , neither of these LPS receptors in plants has been identified so far.

Its fragments, N-acetylchitooligosaccharides, which are released from chitin by plant chitinase digestion during plant—fungus interactions, can serve as elicitors in plant innate immunity Silipo et al. Recent intensive efforts in investigating chitin recognition in plants have reaped progress. In rice, CEBiP a chitin elicitor binding protein , a lysin motif LysM —containing plasma membrane protein, has been identified as the chitin receptor as it can physically bind to chitin and its silencing mutant exhibited significantly impaired chitin responses Kaku et al.

SesshoMaru – KM

Using the lens of athletics to more fully understand the spiritual life Sunday, May 14, Wanda Durant: I write about her as we honor our moms on an unofficial national holiday: Or should we call it “the Real MVP day?! This pregnancy clinic aims to make “choice” a viable and living option. Too often in our country “choice” means terminating a pregnancy in abortion. What if choice meant that a woman and a man understood she would have access to medical and emotional support, personal and professional counseling services, referrals and resources, mentoring, nursing consultants and more.

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Lil Pump – D Rose (Dir. by @_ColeBennett_)